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Micrometastases breast cancer

To determine if micrometastatic disease in the sentinel lymph node is a predictor of non-sentinel lymph node non-SLN involvement in breast cancer. Sentinel lymph node biopsy SLN is an accepted alternative to axillary dissection in staging breast cancer. However, a large subset of patients with metastasis limited to the SLN is unnecessarily subjected to the morbidity of CAD. A retrospective review of prospectively gathered breast cancer patients having SLN was conducted. Patients with metastasis to the SLN were selected for analysis.
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Extensive Lymph Node Removal Doesn't Improve Survival in Some Women with Early-Stage Breast Cancer

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The Implications of Micrometastases in Early-Stage Breast Cancer Revealed

One commonly-used method is sentinel lymph node dissection, where pathologists examine only the lymph node nearest the tumor site to detect any stray cancer cells. If the lymph node contains cancer cells, additional lymph nodes are removed and adjuvant therapy treatment given after surgery is given to kill spreading cancer cells. Unfortunately, the threshold for the amount of cancer that is detected in the sentinel lymph node that is worthy of adjuvant treatment is unclear. And the question physicians face now is what to do when faced with micrometastases, when only a small number of cancer cells are found outside the original tumor site. Strategies can include watch and wait to see if the minimal cancer cells do spread or aggressively treat the patient with adjuvant therapy, which can result in side effects to the patient without clear evidence of benefit.
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The Implications of Micrometastases in Early-Stage Breast Cancer Revealed

October 10, , by NCI Staff. New study results show that for women with early-stage breast cancer, having only a sentinel lymph node biopsy after lumpectomy, rather than a more aggressive biopsy procedure, did not decrease survival. Long-term results from a large clinical trial confirm that, for some women with early-stage breast cancer who have lumpectomy as their surgical treatment, a less extensive lymph node biopsy approach is sufficient.
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Nclark6 wrote:. My pathology report said that I had. I know from research that when cancer is in a lymph node and at least 0.
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